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The mechanism shown below also leads to acyl-oxygen cleavage (see step 5). The mechanism is an example of the less reactive system type. MECHANISM OF THE ACID CATALYSED HYDROLYSIS. Abstract: A series of experiments based on aspirin have been used in our high school chemistry laboratory.
Experiments include (i) synthesis, purification, and characterization of aspirin by mp and TLC, (ii) percentage composition of a commercial aspirin tablet by.
The first step is the slow step—it is the rate-determining step. In it a molecule of tert-butyl chloride ionizes and becomes a tert-butyl cation and a chloride ion.Write a step by step mechanism of aspirin hydrolysis